Diazepam is N-demethylated by CYP3A4 and 2C19 for the active metabolite N-desmethyldiazepam, which is hydroxylated by CYP3A4 for the active metabolite temazepam. N-desmethyldiazepam and temazepam are both of those further more metabolized to oxazepam. Temazepam and oxazepam are largely removed by glucuronidation.Only get this drug as your physician